Jobs at Xenon Pharmaceuticals Inc.

Provides administrative, scientific data management, documentation, inventory, and project coordination support for Discovery operations. Responsibilities include managing calendars, travel, expenses, scientific data uploads, ELN records, reports, inventories, digital workflows, stakeholder communications, and laboratory compliance. The role coordinates with scientific, IT, and operational teams to improve data accuracy, accessibility, and process efficiency in a biopharmaceutical discovery environment.

Supports clinical operations teams in conducting pharmaceutical clinical trials through document review, study start-up, regulatory tracking, eTMF maintenance, trial metrics, sample and supply coordination, vendor and CRO collaboration, invoice processing, meeting support, quality control, audit preparation, and timeline and budget monitoring.

Lead Quality Control activities for clinical and commercial small-molecule drug substance and drug product programs. Manage specifications, stability studies, reference standards, analytical testing, OOS/OOT investigations, release documentation, CMC submission reviews, external laboratories, CMOs, audits, quality systems, and sample transfers. Collaborate across CMC, QA, API, and drug product teams, provide technical development support, and lead team capacity, performance, and deliverables. Domestic and international travel may be required.

The Executive Director, Total Rewards will lead total compensation strategies to attract and retain talent, managing salary, benefits, and recognition programs in a strategic HR role.

The Manager/Senior Manager will lead data management for clinical trials, oversee vendors, design databases, and ensure compliance with regulations.

Leads operational delivery of multiple Phase 3 clinical trials from start-up through closeout. Responsibilities include vendor and CRO selection and oversight, site feasibility, budgets, timelines, risk mitigation, regulatory documentation, cross-functional coordination, compliance with ICH/GCP and applicable regulations, and mentoring junior staff. The role manages trial milestones, quality, and outsourced services while partnering with Clinical Development, Regulatory Affairs, CMC, investigators, and external vendors.

Provide scientific leadership for clinical study design, execution, analysis, and reporting across assigned neuroscience programs. Support protocol development, safety and efficacy data review, regulatory documentation, cross-functional collaboration with CROs and partners, investigator interactions, and development of SOPs and study materials to ensure scientifically rigorous, operationally feasible clinical development.

Lead and coordinate Discovery-stage small molecule programs, manage CROs and contracts, maintain project schedules/budgets, facilitate cross-functional alignment, oversee data workflows and preclinical reporting, and support scientific communications and disclosure processes.

Lead Quality Control for drug substance and product programs from clinical through commercial stages: manage analytical testing, stability programs, reference standards, specifications, OOS/OOT investigations, release and regulatory CMC QC inputs, external lab/CMO oversight, audits, cross-functional collaboration, and supervise staff as needed. Travel up to 20%.