The Mass Spectrometry Expert will design and conduct Mass Spectrometry experiments, analyze data, ensure regulatory compliance, and provide training. Responsibilities include method development for Radioligands, maintaining documentation, and collaborating with teams to achieve project goals.
Job Description Summary
Location: Ivrea, Italy
Role Purpose:
Design, plan and perform Mass Spectrometry experiments as well as report and interpret results/outcome in line with the overall TRD RLT (Radioligand Therapy) project strategy for RLT Drug Substance(s) and Drug Product(s) in development. Ensure project knowledge generation and preparation/timely delivery of supplies with high quality and state of the art standards. Contribute to the analytical project strategy definition; drive scientific and operational excellence and thereby contribute to overall TRD RLT strategy and goals.
Job Description
Major Activities
- As Mass Spec Expert you are responsible for operating our mass spectrometry instruments and conducting analysis of Radioligands samples and training Formulation/Analytical Scientists on Mass Spectrometry topic. You will be part of the RLT Analytical Team at our TRD RLT site in Italy
- Drive, Lead and execute the Liquid Chromatography-Mass Spectrometry (LC-MS) method development and optimization of assigned Radioligands pipeline projects for all relevant sample matrices (Drug Substance, Drug Product). Design experiments, perform risk assessments, and utilize statistical tools to develop robust and reliable analytical methods
- Data Analysis and Interpretation: Analyzing Mass Spectrometry data, interpreting the results, and generating detailed reports summarizing the findings
- Regulatory Compliance: Ensure compliance with regulatory requirements and support filings applying principles described in recent guidelines. Stay updated on evolving regulatory expectations e.g. related to validation strategies
- Documentation and Presentation: Maintaining detailed records of experiments, procedures, and results, and effectively presenting findings through written reports, presentations, and scientific publications
- Collaboration: Working closely with other scientific and technical staff to design experiments, interpret results, and provide expertise in Mass Spectrometry techniques
- Follow the appropriate SOP’s, GLP, GMP, OQM, HSE, ISEC and Novartis guidelines
- Exhibit strong team spirit and promote knowledge exchange
Ideal Background
Education:
- Minimum: Master’s degree (ideally PhD) in Analytical Chemistry, Chemistry, Pharmaceutical Technology, or equivalent scientific degree with minimum 2 years of successful industry experience and/or proven experience with strong hands-on in the field of Mass Spectrometry characterization and method development.
Languages:
- Fluent knowledge of English (oral and written). Desirable knowledge of site language (Italian).
Experience / Professional requirements:
- Experience with small molecules characterization will be an advantage and highly appreciated
- Experience with Liquid Chromatography method development
- Experience with different Mass Spectrometry data processing software will be an advantage (e.g. Chromeleon, Freestyle, XCalibur, Genedata, Compound Discoverer)
- Awareness for safe handling of chemicals, potentially dangerous materials, and equipment
- Excellent analytical and problem-solving skills, and a meticulous approach to laboratory work
Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.
Skills Desired
Top Skills
Liquid Chromatography
Mass Spectrometry
Similar Jobs
Healthtech
The Advanced Analytics Lead will drive the advanced analytics agenda within the region, applying statistical techniques and machine learning to improve sales, marketing, and operational strategies. This role will collaborate with cross-functional teams, manage AI/ML initiatives, and develop a scalable analytics pipeline, ensuring data-driven solutions are impactful and efficient.
Top Skills:
AlteryxPythonR
Biotech • Pharmaceutical
The RLT Analytical Expert will design and plan scientific experiments, report and interpret results, contribute to project strategy, and ensure the timely delivery of high-quality supplies while adhering to regulatory guidelines. Responsibilities include coordinating analytical activities, authoring documents, and supporting method execution in accordance with safety and quality standards.
Top Skills:
Analytical ChemistryRadiochemistry
Automotive • Other
The Senior Data Scientist will design and implement cutting-edge AI models, particularly focusing on Large Language Models (LLMs) for speech recognition and text-to-speech applications. Responsibilities include collaborating with teams, optimizing models, and staying updated with AI advancements to enhance system performance.
Top Skills:
Python
What you need to know about the Vancouver Tech Scene
Raincouver, Vancity, The Big Smoke — Vancouver is known by many names, and in recent years, it has gained a reputation as a growing hub for both tech and sustainability. Renowned for its natural beauty, the city has become a magnet for professionals eager to create environmental solutions, and with an emphasis on clean technology, renewable energy and environmental innovation, it's attracted companies across various industries, all working toward a shared goal: advancing clean technology.
