The ECMO Perfusionist will manage whole-body perfusion procedures, evaluate physiological injury from cryopreservation, and improve recovery outcomes through protocol modifications.
About Until
Until is a moonshot company building a “pause button” for biology. Our near-term focus is organ-scale reversible cryopreservation: preserving donated organs at subzero temperatures without ice formation, then rewarming them uniformly for transplant. By solving this challenge, we are laying the foundation for whole-body reversible cryopreservation, giving patients a bridge to future cures.
To achieve our goal, we are assembling an interdisciplinary team to develop perfusion systems, cryoprotectant formulations, and vitrification and rewarming hardware.
We envision a future where no transplantable organ is lost to logistics, and no terminal diagnosis is final because patients can safely wait for future medicine to arrive.
About the Role
We are seeking a highly skilled ECMO Perfusionist to support preclinical rodent studies involving extracorporeal membrane oxygenation (ECMO) and cardiopulmonary bypass systems. Our studies involve transitioning animals from normothermic blood perfusion to hypothermic, non-blood perfusion with cryoprotectant solutions, followed by controlled rewarming and reperfusion with blood. Each phase presents distinct physiological and biochemical challenges that can impact organ viability and whole-body recovery.
This position extends beyond traditional ECMO management and requires deep physiological insight, strong troubleshooting skills, and protocol optimization experience. The perfusionist will be responsible for identifying key failure points, diagnosing mechanisms of injury, and proposing meaningful protocol modifications to improve recovery outcomes.
Key Responsibilities
- Oversee and manage whole-body perfusion procedures, systematically identifying critical procedural variables that can be optimized to improve overall animal health and recovery outcomes.
- Evaluate and diagnose physiological injury resulting from cryoprotectant exposure and temperature transitions during cryopreservation, including organ-specific and systemic effects.
- Develop and recommend data-driven modifications to cryoprotectant formulations, perfusion parameters, and cryopreservation protocols to enhance safety, reduce tissue damage, and improve whole-body resuscitation post cryopreservation.
Qualifications
- 3+ years ECMO perfusion experience
- Demonstrated a passion for rapid problem solving and success working through novel hard problems
- Desire to work in a laboratory setting
Similar Jobs
Cloud • Greentech • Social Impact • Software • Consulting
The Senior Product Marketing Manager drives market strategies, aligns sales and marketing, develops messaging, and enables customer success teams to enhance market share and drive growth in the B2B SaaS space.
Top Skills:
B2B SaasProduct Management Frameworks
Blockchain • Fintech • Payments • Financial Services • Cryptocurrency • Web3
As a Staff IT Engineer, you will improve Circle's enterprise IT systems, manage critical platforms, and drive automation initiatives while ensuring high-quality IT services and executive-level support.
Top Skills:
IrumacOSN8NServicenow ItsmWindowsWorkatoWorkspace One
Artificial Intelligence • Hardware • Healthtech • Software
Lead the talent acquisition function, evolving it into a data-driven process while enhancing candidate experiences and employer branding during hyper-growth.
Top Skills:
Ai WorkflowsAtsRecruiting Analytics
What you need to know about the Vancouver Tech Scene
Raincouver, Vancity, The Big Smoke — Vancouver is known by many names, and in recent years, it has gained a reputation as a growing hub for both tech and sustainability. Renowned for its natural beauty, the city has become a magnet for professionals eager to create environmental solutions, and with an emphasis on clean technology, renewable energy and environmental innovation, it's attracted companies across various industries, all working toward a shared goal: advancing clean technology.
